Identification of a follicle-stimulating hormone receptor-binding region in hFSH-beta-(81-95) using synthetic peptides.
نویسندگان
چکیده
منابع مشابه
Properties of follicle-stimulating hormone-receptor interactions. Specific binding of human follicle-stimulating hormone to rat testes.
Some properties of the interaction between radioiodinated human follicle stimulating hormone (lz51-hFSH) and its specific receptors in preparations of rat seminiferous tubule homogenate are described. Specific binding of lz51-hFSH by seminiferous tubule homogenate was appreciably greater than to Leydig cell homogenate of rat testes. The uptake of rz51-hFSH was hormone specific and uptake inhibi...
متن کاملIdentification and Characterization of Contact Sites between Human Follicle Stimulating Hormone and the Follicle Stimulating Hormone Receptor
OF DISSERTATION
متن کاملConversion of human choriogonadotropin into a follitropin by protein engineering.
Human reproduction is dependent upon the actions of follicle-stimulating hormone (hFSH), luteinizing hormone (hLH), and chorionic gonadotropin (hCG). While the alpha subunits of these heterodimeric proteins can be interchanged without effect on receptor-binding specificity, their beta subunits differ and direct hormone binding to either LH/CG or FSH receptors. Previous studies employing chemica...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1990
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)34080-3